Automated Dissolution Systems

The Hanson AutoPlus precision syringe-pump sampling system provides inert Teflon(1) sampling tubing and valves that peri-pumps cannot. Peri-pumps, by their design, require plastic-type tubing which deforms with simple normal use. This requires continuous recalibration (often once a month!), tubing “tweaks” and maintenance hassles, and frequent system qualification. Additionally, plastic tubing often distorts drug analysis because of plasticizers and/or drug absorption problems. The Hanson AutoPlus avoids these peri-pump

deficiencies by employing a precision syringe-pump with both life and volume accuracy ten times better(2) than a peri-pump. Not only is the AutoPlus system inert for use in your dissolution lab, but a simple calibration is recommended only once a year… and its tubing lasts for years. Lastly, the AutoPlus delivers performance capabilities that peri-pumps cannot, including multi-bath routines with media replace, dilution and pH change, multiple standards, precision accuracy, and advanced user-friendly protocols.

1     Teflon and/or inert equivalent (e.g. PEEK, EPDM)
2     AutoPlus typically requires calibration 1/year; peri-pumps 1/month (1:12)
       AutoPlus tubing typically lasts 5 years; peri-pumps 6 months (1:10)
       AutoPlus volume accuracy & repeatability after one year +/- 1%; peri-pumps +/- 10% (estimate, 1:10)

How the System Works