AutoPlus™ On-Line UV/VIS Autosampler

The Hanson AutoPlus™ is a new precision syringe-pump sampling system for dissolution testing and analysis. The AutoPlus represents thirty years of dissolution test know-how at Hanson Research. We were the first in the business with a dissolution bath in 1969 and a fully automated dissolution test system in 1975. Our precision syringe-pump sampling systems began with the Microette™ in 1991, and were enhanced with the Waters™ Transfer Module in 1998. These new AutoPlus systems bring autosampling power, performance and throughput to the modern pharmaceutical lab that is unequaled in the dissolution industry.

The basic AutoPlus platform consists of a choice of 6 or 8 precision glass sampling syringes, with internal valve interfacing, driven by a stepper motor control, in one compact ergonomic instrument package. Teflon tubing harnesses connect up to 3 dissolution baths, along with multi-cell changers for on-line UV/VIS sample analysis, as well as collection trays for sample archive.

Easy-Icon™ programming with graphical display provides a wide range of dissolution test applications, including detect and collect, multi-bath sampling, and routines for set-up, cleaning, validation, 21CFR11, and diagnostics.

The AutoPlus is designed to interface with the Agilent 8453 ChemStation and other modern spectrophotometers with multi-cell capability, and includes communications protocols via contact closure, RS232 and dynamic data exchange (DDE). Similar to the Hanson SR8-Plus “virtual instrument” programming, the AutoPlus is a smart device that anticipates user requirements for set-up, test run, sample throughput and validation. User-friendly features include protocol memory with password protection, continuous display of test conditions and status, user prompts and help screens (ideal for training). The AutoPlus maximizes laboratory efficiency by handling extensive methods, problem drugs, surfactants and other media.