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The vertical diffusion cell, first popularized by Dr. Thomas Franz, has been applied to a number
of skin permeation studies, including topical and transdermal drug delivery formulations, as well
as opthalmics, cosmetics, skin care products and pesticides. The vertical diffusion cell system is
an ideal tool for quality control of topical preparations (see FDA guideline SUPAC SS). The Hanson
vertical diffusion cell is newly redesigned for accuracy and ease of use, based on over fifteen
years of rigorous industry, university and regulatory application.
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Precision glass cell assemblies include receptor chamber, donor chamber with easy-use clamp,
dosage wafer (300 mg "infinite dose" or other volumes available), sampling and media replace ports,
outside jacket for temperature control, and Helix™ stirrer. Cells may be manually sampled, or
automated with the MicroettePlus. Cells are designed to be "occluded" (sealing the donor from air)
to minimize any back-diffusion from automated sampling. Cells include individual serial numbers,
and are available in three convenient sizes.
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